The Central Role of Survivin in Proliferation and Apoptosis of Malignant Pleural Mesothelioma
نویسندگان
چکیده
Malignant pleural mesothelioma is the most common mesothelial malignancy, which arises from the malignant transformation of mesothelial cells that line the pleural cavity. Malignant pleural mesothelioma is a highly invasive disease with a very long latency and treatment is rarely effective, since only few patients survive more than one year after diagnosis (Carbone et al., 2007). Asbestos, a fibrous mineral widely used throughout the 20th century, has been acknowledged to being the main causative agent (Wagner, 1979).
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